Preheat the oven to 400 degrees F (200 degrees C). Grease or line a baking sheet with parchment paper.
Stir flour, Cheddar cheese, baking powder, salt, and garlic powder together in a bowl.
Stir milk, softened butter pieces, and egg together in a separate bowl. Add to the flour mixture and stir until just combined and chunky, being very careful not to overmix.
Drop batter by tablespoonfuls onto the prepared baking sheet.
Bake in the preheated oven for 10 minutes.
Meanwhile, stir melted butter, parsley, and garlic powder together in a small bowl. Remove biscuits from the oven and brush melted butter mixture over top.
Return to the oven and bake until golden brown, about 5 more minutes. Serve warm.